Statins in Acute Coronary Syndromes and Genetic Insight
نویسندگان
چکیده
منابع مشابه
Statins in acute coronary syndromes.
Statins are the main resource available to reduce LDL-cholesterol levels. Their continuous use decreases cardiovascular morbidity and mortality due to atherosclerosis. The administration of these medications demonstrated to be effective in primary and secondary prevention clinical trials in low and high risk patients. Specialists believe that a possible benefit of hypolipidemic therapy in preve...
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This review examines the use of HMG-CoA reductase inhibitor (statin) medications early in the clinical course of acute coronary syndrome. Available data demonstrate that there are clear clinical benefits to this practice. Numerous previous studies have documented the primary and secondary benefits of statins in the prevention of coronary events. Recent trials show that when statins are used dur...
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Coronary Syndromes To the Editor: In a recent article,1 we reported that pretreatment with statins before onset of symptoms in patients with acute coronary syndromes is associated with significantly improved clinical outcomes, and that discontinuation of statin therapy after onset of symptoms completely abrogates the beneficial effect of statin therapy. We have reevaluated our data and found in...
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The past decade has witnessed revolutionary changes in the understanding of the pathogenesis and management of acute coronary syndromes (ACS). The major cause of ACS is the rupture or erosion of an atherosclerotic plaque and subsequent thrombosis leading to variable obstruction in the coronary arterial lumen. Clinical strategies for the management of ACS now focus more on creating plaque stabil...
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Introduction: Coronary artery disease (CAD) is among the most common, serious, chronic and life- threatening illnesses in the world. CAD represents a spectrum of conditions, with acute myocardial infarction at one end of it and silent ischemia at the other. There is growing evidence on importance of prognosis of C- reactive protein (CPR) in unstable angina and this protein is a maker of an adve...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2010
ISSN: 0735-1097
DOI: 10.1016/j.jacc.2009.12.020